Music is known as one of the great brain simulators and Radiolab podcasts are known for their innovative sound design. This fascinating, sound extravaganza podcast makes for a perfect combination. There are few musical moments more well-worn than the first four notes of Beethoven’s Fifth Symphony. But in this episode, hosts Jad Abumrad and Robert Krulwic find out that Beethoven might have made a last-ditch effort to keep his music from ever feeling familiar, to keep pushing his listeners to a kind of psychological limit. Featuring the Brooklyn Philharmonic Orchestra.